The Position
We are seeking a Director, FP&A to serve as a strategic finance partner to our R&D organization. In this highly visible role, you will support critical investment decisions across our development portfolio by delivering financial insights, forecasting, and decision support.
You’ll work closely with R&D and finance leadership to translate scientific and clinical strategies into actionable financial plans, helping ensure resources are deployed effectively across programs.
This role reports to the Sr. Director of FP&A and follows a hybrid scheduled of two-to-three days per week in office.
The Impact You’ll Have
Strategic Partnership & Decision Support
- Partner with R&D leadership and project teams to develop portfolio and program-level financial plans
- Lead scenario modeling, cost-benefit analyses, and vendor investment decisions
- Support clinical program investment decisions and other high-priority strategic initiatives
Financial Planning & Analysis
- Deliver accurate and timely forecasts, budgets, and long-range plans for R&D functions
- Prepare and present financial analyses to senior leadership, including materials for Board meetings
- Provide variance analysis and actionable insights to inform decision-making
Cross-Functional Collaboration
- Partner closely with Accounting to align budget vs actuals, including accruals, coding, and variance reporting
- Collaborate with functional stakeholders to translate scientific and operational plans into financial outcomes
Process Improvement & Systems
- Drive improvements in FP&A processes, reporting, and forecasting accuracy
- Partner with the Head of FP&A to enhance and automate allocation methodologies across programs and indications
As a Director, we also expect our leaders to demonstrate the following Leadership Competencies:
- Communication and Influence
- Builds communication channels across Maze for sharing information.
- Influences Senior Management decisions through persuasive arguments.
- Respectfully addresses differing opinions leading to support of decisions.
- Teamwork and Collaboration
- Champions partnerships and connections across Maze.
- Proactively addresses issues that could result in breakdown of team relationships.
- Spotlights team and individual contributions in public forums.
- Execution and Results
- Addresses gaps and leverages strengths to get best results.
- Maintains a steadying presence and clarifies priorities during change.
- Anticipates and removes barriers that put functional/corporate goals at risk.
- Develop Others and Self
- Remove barriers to staff development and empowers them to make their own decisions.
- Stays current on industry trends and keeps direct-reports prepared and responsive.
What We’re Looking For
Experience & Background
- Bachelor’s degree in Finance, Accounting, Economics, or related field; MBA or equivalent experience preferred.
- 10+ years of experience in the pharmaceutical or biotech industry, including significant FP&A experience
- Experience supporting R&D or development organizations strongly preferred
- Clinical trial forecasting and accruals experience preferred
Technical & Analytical Skills
- Advanced proficiency in Excel and PowerPoint
- Experience with financial systems such as NetSuite, Coupa, and Anaplan, or similar tools
- Strong financial modeling and forecasting capabilities, including ad hoc analysis
Business Partnership & Communications
- Proven ability to build strong relationships and influence cross-functional stakeholders
- Ability to translate complex scientific and strategic concepts into clear financial insights
- Excellent written and verbal communication
Execution & Mindset
- Highly organized with the ability to manage multiple priorities and meet deadlines
- Detail-oriented and solution-driven, with a focus on continuous improvement
- Collaborative mindset with a focus on improving efficiency and effectiveness
- Interest in exploring applications of AI to enhance FP&A processes
This role follows a hybrid schedule, with an expectation to be onsite at our South San Francisco headquarters two-to-three days per week.
About Maze Therapeutics
Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing human genetics to develop precision medicines for patients with kidney and metabolic diseases. Our clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1‑mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease. We are also advancing a preclinical pipeline through our Compass platform, which links human genetic variants to the biological pathways that drive disease.
Our People
Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients.
Our Core Values
Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission.
Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.
Stand True – Our integrity is foundational; it guides us no matter the obstacle.
The expected annual salary range for employees located in the San Francisco Bay Area is $227,000 to $277,000. Additionally, this position is eligible for an annual performance bonus.
Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future.
Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy.
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